MRPL22 Polyclonal Antibody

SKU: E-AB-53083

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MRPL22

Target Synonym:MRPL22;39S ribosomal protein L22;39S ribosomal protein L22 mitochondrial precursor;39S ribosomal protein L25;39S ribosomal protein L25; mitochondrial;E030011D16Rik;HSPC158;L22mt;L25mt;mitochondrial;mitochondrial ribosomal protein L22;MRP L22;MRP L25;MRP-L22;MRP-L25;Mrpl22;RM22;RPML25

Research Areas:Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9NWU5

Accession:

Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.

Concentration:1.02 mg/mL

Immunogen:Fusion protein of human MRPL22

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:24 kDa

ObservedMW:Refer to figures