MRAP2 Antibody, Biotin conjugated - Cat. #: CSB-PA853421LD01HU

SKU: CSB-PA853421LD01HU

Size :50ug

Clone Number:

Aliases:MRAP2 antibody; C6orf117 antibody; Melanocortin-2 receptor accessory protein 2 antibody; MC2R accessory protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96G30

Immunogen:Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MRAP2

Research Areas:Neuroscience; Signal transduction