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GeneBio Systems

MPG Polyclonal Antibody

MPG Polyclonal Antibody

SKU:E-AB-14767

Regular price €493,95 EUR
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MPG

Target Synonym: 3 alkyladenine DNA glycosylase;3-alkyladenine DNA glycosylase;3-methyladenine DNA glycosidase;3MG;AAG;ADPG;Alkyladenine DNA glycosylase;anpg;APNG;CRA36.1;DNA 3 methyladenine glycosylase;DNA-3-methyladenine glycosylase;MDG;Mid1;Mpg;N methylpurine DNA glycosirase;N methylpurine DNA glycosylase;N-methylpurine-DNA glycosylase;PIG11;PIG16;Proliferation inducing protein 11;Proliferation inducing protein 16

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P29372

Accession:

Background: Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase). Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.

Concentration: 0.7 mg/mL

Immunogen: Recombinant protein of human MPG

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:1000-1:5000

Calculated MW: 32kDa

ObservedMW:

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