Mouse visfatin,NAMPT ELISA KIT

SKU: E0597Mo

Size:96 Tests-1 Kit

Background:The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma (By similarity). Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. {ECO:0000250|UniProtKB:P43490, ECO:0000269|PubMed:12555668, ECO:0000269|PubMed:15381699, ECO:0000269|PubMed:19286518, ECO:0000269|PubMed:19299583}.

Research_area:

Applications:ELISA

Target_protein:Nampt

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.46ng/ml

Detection range:1-400ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:visfatin

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q99KQ4

MASS(Da):55447

GeneID:59027

Synonyms:Nampt Pbef1

Gene names:Nampt

Standard solution:480ng/ml