Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B, TNFRSF10B ELISA Kit

SKU: E2536Mo

Size:96 Tests-1 Kit

Background:Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

Research_area:Cell Biology; Signal Transduction; Cancer; Cardiovascular

Applications:ELISA

Target_protein:TNFRSF10B

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.124ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Tumor necrosis factor receptor superfamily member 10B

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9QZM4

MASS(Da):42,165

GeneID:21933

Synonyms:CD antigen CD262;Death receptor 5;DR;DR5;KI;Kille;KILLER;Ly9;Ly98;MK;TNFRSF10B;TR;TRAILR2;TRIC;TRICK;TRICK2A;TRICK2B;TRICKB;Tumor necrosis factor receptor superfamily member 10B

Gene names:Tnfrsf10b

Standard solution:96ng/mL