Mouse TNFRSF14/HVEM ELISA Kit PicoKine®

SKU: EK1227

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: TNFRSF14

Specificity: Natural and recombinant mouse TNFRSF14

Background: Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as HVEM, is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. It is mapped to 1p36.32. HVEM plays an important role in HSV pathogenesis because it enhanced the entry of several wildtype HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T cells. HVEM and BTLA which are form a biional signaling pathway can regulate cell survival and inhibitory responses between interacting cells. HVEM as an important orchestrator of mucosal immunity integrates signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicated that targeting HVEM with agonists could improve host defense.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Q29-V207

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: Q80WM9

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 230979

Protein Name: Tumor necrosis factor receptor superfamily member 14

Gene Full Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

Synonyms: ATAR; Herpes virus entry mediator A; Herpesvirus entry mediator A; HVEA; HVEM; LIGHTR; TNFRSF14; TR2