Mouse Thioredoxin Reductase 1, TXNRD1 ELISA Kit

SKU: E2596Mo

Size:96 Tests-1 Kit

Background:Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Research_area:Others

Applications:ELISA

Target_protein:TXNRD1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.019ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Thioredoxin Reductase 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9JMH6

MASS(Da):67,084

GeneID:50493

Synonyms:Thioredoxin reductase 1, cytoplasmic;Thioredoxin reductase TR1;TR;TR1;Trx;TrxR1;TXNRD1

Gene names:Txnrd1

Standard solution:24ng/ml