Mouse Semaphorin-4D, SEMA4D ELISA Kit

SKU: E2453Mo

Size:96 Tests-1 Kit

Background:Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (By similarity). Regulates GABAergic synapse development (PubMed: 23699507, PubMed: 29981480). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (PubMed: 23699507, PubMed: 29981480). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (By similarity). Promotes the migration of cerebellar granule cells (PubMed: 17554007). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (By similarity). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:SEMA4D

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.056ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Semaphorin-4D

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O09126

MASS(Da):95,640

GeneID:20354

Synonyms:CD antigen CD100;M-Sema G;SEMA 4D;Sema J;SEMA4D;Semaphorin-4D;Semaphorin-C-like 2;Semaphorin-J

Gene names:SEMA4D

Standard solution:48ng/mL