Mouse Secreted Frizzled Related Protein 1, SFRP1 ELISA Kit

SKU: E0902Mo

Size:96 Tests-1 Kit

Background:Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription (By similarity).

Research_area:Cell Biology; Neuroscience; Stem Cells; Developmental Biology

Applications:ELISA

Target_protein:SFRP1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.29ng/mL

Detection range:10-2000ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Secreted Frizzled Related Protein 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8C4U3

MASS(Da):35,413

GeneID:20377

Synonyms:Secreted frizzled-related protein 1;SFRP 1;SFRP1;sFRP-1

Gene names:SFRP1

Standard solution:2400ng/mL