Mouse SAP/PTX2/APCS EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ1208

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: APCS

Specificity: Natural and recombinant mouse SAP

Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called amyloid. It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q21-D224

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Reconstitution:

Reference:

Uniprot ID: P12246

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 20219

Protein Name: Serum amyloid P-component

Gene Full Name: amyloid P component, serum

Synonyms: 9.5S alpha 1 glycoprotein; amyloid P component; serum; APCS; PTX2; SAP; Serum amyloid P component