Mouse PGLYRP1/Pgrps ELISA Kit PicoKine®

SKU: EK1618

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Pglyrp1

Specificity: Natural and recombinant mouse PGLYRP1

Background: Peptidoglycan recognition protein 1, also known as TAG7, is a protein that in humans is encoded by the PGLYRP1 gene. The PGLYRP1 gene is highly expressed in bone marrow, circulating Polymorphonuclear leukocytes (PMLs), and in the corneal epithelium. The PGLYRP1 protein is primarily found in the granules of PMLs. The PGLYRP1 protein plays an important role in the innate immune response. It is bactericidal against gram-positive bacteria such as S. aureus, S. epidermidis, and L. monocytogenes and generally has proinflammatory effects, inducing TNF-a and IFN-g in many tissues. PGLYRP-1 is also known to form a cytotoxic complex with HSP-70, suggesting it may also have a role in anti-cancer defense. As a pathogen recognition protein with antimicrobial properties, PGLYRP-1 is suspected to play an important role in maintaining the gut microbial flora.

Immunogen: Expression system for standard: NS0; Immunogen sequence: F19-E182

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Reference:

Uniprot ID: O88593

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 21946

Protein Name: Peptidoglycan recognition protein 1

Gene Full Name: peptidoglycan recognition protein 1

Synonyms: Peptidoglycan recognition protein 1; Cytokine tag7; Peptidoglycan recognition protein short; PGRP-S; Pglyrp1; Pglyrp; Pgrp; Pgrps; Tag7