Mouse Metastasis-Suppressor Kiss-1, KISS1 ELISA Kit

SKU: E2253Mo

Size:96 Tests-1 Kit

Background:Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated Peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.

Research_area:Others

Applications:ELISA

Target_protein:KISS1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:3.45ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Metastasis-Suppressor Kiss-1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6Y4S4

MASS(Da):14,117

GeneID:280287

Synonyms:KISS 1;KISS1;Kisspeptin-1;Kisspeptin-10;Kisspeptin-52;Metastasis-suppressor KiSS-1;Metastin;Metastin45-54

Gene names:KISS1

Standard solution:1600ng/L