Mouse IL-17 High Sensitivity ELISA Kit PicoKine®

SKU: HSEK0431

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: IL17A

Specificity: Natural and recombinant mouse IL-17/IL-17A

Background: IL-17 is an inflammatory cytokine produced primarily by a unique lineage of CD4 T cells that plays critical roles in the pathogenesis of multiple autoimmune diseases. Interleukin-17 is expressed by activated T cells and is 57% identical to the 17- to 26-kD secretory glycoprotein encoded by gene 13 of the herpesvirus saimiri (HVS-13). IL17 induces nuclear factor kappa-B and the expression of IL6, intercellular adhesion molecule-1, granulocyte macrophage colony-stimulating factor,and prostaglandin E2, as well as the maturation of CD34 positive hematopoietic precursors into neutrophils. Anti-IL17 antibodies significantly inhibited osteoclast formation induced by culture media of RA synovial tissues. The standard product used in this kit is recombinant mouse IL-17, consisting of 137 amino acids with the molecular mass of 15.5KDa.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: T22-A158

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Reference:

Uniprot ID: Q544E6

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 16171

Protein Name: Interleukin 17A

Gene Full Name: interleukin 17A

Synonyms: Interleukin 17A ; Il17a ; Il17 ; mCG_7914