Mouse CTLA4 PicoKine® Quick ELISA Kit

SKU: FEK0717

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Ctla4

Specificity: Natural and recombinant Mouse Ctla4

Background: CTLA-4(Cytotoxic T-Lymphocyte Antigen 4), also known as CD152(Cluster of differentiation 152), is a protein receptor that down regulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.

Immunogen: Expression system for standard: NS0; Immunogen sequence: A37-F162

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Uniprot ID: P09793

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 12477

Protein Name: Cytotoxic T-lymphocyte protein 4

Gene Full Name: cytotoxic T-lymphocyte-associated protein 4

Synonyms: CD152; CTLA 4; CTLA4; Ly 56