Mouse Coronin 1C,CORO1C ELISA KIT

SKU: E1056Mo

Size:96 Tests-1 Kit

Background:Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed:25074804, PubMed:25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed:25074804, PubMed:25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (PubMed:27178841). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (PubMed:27178841). Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (By similarity). Required for normal distribution of mitochondria within cells (PubMed:27178841). {ECO:0000250|UniProtKB:Q9ULV4, ECO:0000269|PubMed:25074804, ECO:0000269|PubMed:25925950, ECO:0000269|PubMed:27178841}.

Research_area:

Applications:ELISA

Target_protein:Coro1c

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.08ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Coronin 1C

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9WUM4

MASS(Da):53121

GeneID:23790

Synonyms:Coro1c

Gene names:Coro1c

Standard solution:24ng/ml