Mouse C-C Motif Chemokine 2, CCL2 ELISA Kit

SKU: E1707Mo

Size:96 Tests-1 Kit

Background:Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (PubMed: 29993042). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (PubMed: 29993042).

Research_area:Immunology

Applications:ELISA

Target_protein:CCL2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.93pg/ml

Detection range:2-600pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:C-C Motif Chemokine 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10148

MASS(Da):16,326

GeneID:20296

Synonyms:C-C motif chemokine 2;CCL 2;CCL2;MCP-1;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;Platelet-derived growth factor-inducible protein JE;Small-inducible cytokine A2

Gene names:CCL2

Standard solution:800pg/ml