Mouse Beta-Site APP Cleaving Enzyme 1,bACE1 ELISA KIT

SKU: E1559Mo

Size:96 Tests-1 Kit

Background:Responsible for the proteolytic processing of the amyloid precursor protein (APP) (PubMed:29325091). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:29325091). Cleaves CHL1 (PubMed:29325091). {ECO:0000269|PubMed:29325091}.

Research_area:

Applications:ELISA

Target_protein:Bace1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.053ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Beta-Site APP Cleaving Enzyme 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P56818

MASS(Da):55748

GeneID:23821

Synonyms:Bace1 Bace

Gene names:Bace1

Standard solution:48ng/ml