Mouse AXL ELISA Kit PicoKine®

SKU: EK0660

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: AXL

Specificity: Natural and recombinant mouse AXL

Background: Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene, which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants.

Immunogen: Expression system for standard: NS0; Immunogen sequence: H20-P443

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Reference:

Uniprot ID: Q00993

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 26362

Protein Name: Tyrosine-protein kinase receptor UFO

Gene Full Name: AXL receptor tyrosine kinase

Synonyms: AXL; AXL oncogene; AXL receptor tyrosine kinase; JTK11; UFO