Mouse Autophagy related protein 16-like 1,ATG16L1 ELISA KIT

SKU: E2647Mo

Size:96 Tests-1 Kit

Background:Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:18849966, PubMed:12665549, PubMed:24954904, PubMed:24553140, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (By similarity). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway. Plays a role in regulating morphology and function of Paneth cell. {ECO:0000250|UniProtKB:Q676U5, ECO:0000269|PubMed:12665549, ECO:0000269|PubMed:18849966, ECO:0000269|PubMed:23392225, ECO:0000269|PubMed:24238340, ECO:0000269|PubMed:24553140, ECO:0000269|PubMed:24954904}.

Research_area:

Applications:ELISA

Target_protein:Atg16l1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:11.44ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Autophagy related protein 16-like 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8C0J2

MASS(Da):68172

GeneID:77040

Synonyms:Atg16l1 Apg16l

Gene names:Atg16l1

Standard solution:4000ng/L