Mouse Atrial natriuretic peptide-converting enzyme,CORIN ELISA KIT

SKU: E1232Mo

Size:96 Tests-1 Kit

Background:Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) processing (PubMed:11884416, PubMed:15637153). Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (PubMed:11884416, PubMed:15637153, PubMed:22418978). Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (PubMed:22437503). Also acts as a regulator of sodium reabsorption in kidney (PubMed:20613715, PubMed:22418978). May also process pro-NPPB the B-type natriuretic peptide (By similarity). {ECO:0000250|UniProtKB:Q9Y5Q5, ECO:0000269|PubMed:11884416, ECO:0000269|PubMed:15637153, ECO:0000269|PubMed:20613715, ECO:0000269|PubMed:22418978, ECO:0000269|PubMed:22437503}.

Research_area:

Applications:ELISA

Target_protein:Corin

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:8.18pg/ml

Detection range:18.75-1200pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Atrial natriuretic peptide-converting enzyme

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Z319

MASS(Da):123006

GeneID:53419

Synonyms:Corin Crn Lrp4

Gene names:Corin

Standard solution:2400pg/ml