MMP9 Monoclonal Antibody

SKU: BT-MCA4714

Size:100μL

Background:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Research_area:Cardiovascular

Target_protein:MMP9

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5C3

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:MMP9

Immunogen:Purified recombinant fragment of human MMP9 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):92kDa

UniProt accession:P14780

Synonyms:GELB, CLG4B, MMP-9, MANDP2

GeneID:4318