Mmp13 Antibody, Biotin conjugated - Cat. #: CSB-PA17739D0Rb

SKU: CSB-PA17739D0Rb

Size :50ug

Clone Number:

Aliases:Mmp13 antibody; Collagenase 3 antibody; EC 3.4.24.- antibody; Matrix metalloproteinase-13 antibody; MMP-13 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:P33435

Immunogen:Recombinant Mouse Collagenase 3 protein (105-472AA)

Raised in:Rabbit

Species Reactivity:Mouse

Tested Applications:ELISA

Background:Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Mmp13

Research Areas:Cancer; Cardiovascular; Cell biology; Signal transduction