MITF Polyclonal Antibody

SKU: E-AB-60287

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MITF

Target Synonym:MITF;CMM8;COMMAD;MI;WS2;WS2A;bHLHe32

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O75030

Accession:

Background:This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human MITF (NP_937801.1).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:40kDa/46kDa/52kDa/55kDa/56kDa/57kDa/58kDa

ObservedMW:65kDa