MICAL1 antibody , Cat. # FNab05177

SKU: FNab05177

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.

Immunogen:microtubule associated monoxygenase, calponin and LIM domain containing 1

Synonyms:MICAL, MICAL 1, MICAL1, NICAL

Observed MW:120 kDa

Uniprot ID:Q8TDZ2

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IHC, IP, FC

Recommended dilution:WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Gene ID:64780

Research Area:Signal Transduction, Metabolism, Developmental biology