MEF2A Antibody, Biotin conjugated - Cat. #: CSB-PA013670LD01HU

SKU: CSB-PA013670LD01HU

Size :50ul

Clone Number:

Aliases:ADCAD1 antibody; MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody; MEF2 antibody; MEF2A antibody; MEF2A_HUMAN antibody; Myocyte enhancer factor 2A antibody; Myocyte-specific enhancer factor 2A antibody; RSRFC4 antibody; RSRFC9 antibody; Serum response factor like protein 1 antibody; Serum response factor-like protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q02078

Immunogen:Recombinant Human Myocyte-specific enhancer factor 2A protein (72-226AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Transcriptional activator which binds specifically to the MEF2 element, 5\'-YTA[AT](4)TAR-3\', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MEF2A

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cardiovascular; Signal transduction; Stem cells