MECOM Polyclonal Antibody

SKU: E-AB-19826

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MECOM

Target Synonym: Ecotropic Virus Integration Site 1 Protein Homolog;MDS1 And EVI1 Complex Locus Protein;PR Domain 3;EVI1;MDS1;MDS1 And EVI1 Complex Locus Protein EVI1;MDS1 And EVI1 Complex Locus Protein MDS1;Ecotropic Viral Integration Site 1;Myelodysplasia Syndrome 1 Protein;Zinc Finger Protein Evi1;Oncogene EVI1;AML1-EVI-1;MDS1-EVI1;RUSAT2;KMT8E;PRDM3

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q03112

Accession:

Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Concentration: 1.68 mg/mL

Immunogen: Synthetic peptide of human MECOM

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:40-1:200

Calculated MW:

ObservedMW: