MCRS1 Antibody - Cat. #: CSB-PA013611LA01HU

SKU: CSB-PA013611LA01HU

Size :50ug

Clone Number:

Aliases:58 kDa microspherule protein antibody; Cell cycle regulated factor (78 kDa) antibody; Cell cycle regulated factor p78 antibody; Cell cycle-regulated factor p78 antibody; ICP22BP antibody; INO80 complex subunit J antibody; MCRS 1 antibody; MCRS 2 antibody; MCRS1 antibody; MCRS1_HUMAN antibody; MCRS2 antibody; Microspherule protein 1 antibody; MSP 58 antibody; MSP58 antibody; p78 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96EZ8

Immunogen:Recombinant Human Microspherule protein 1 protein (1-138AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MCRS1

Research Areas:Epigenetics and Nuclear Signaling