MCM2 Monoclonal Antibody

SKU: BT-MCA2202

Size:100μL

Background:The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:MCM2

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:1E7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MCM2

Immunogen:Purified recombinant fragment of human MCM2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):125kDa

UniProt accession:P49736

Synonyms:BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN, KIAA0030, MGC10606

GeneID:4171