MBTPS2 Antibody - Cat. #: CSB-PA905280

SKU: CSB-PA905280

Size :100ul

Clone Number:

Aliases:BRESEK antibody; Endopeptidase S2P antibody; IFAP antibody; KFSDX antibody; MBTP2_HUMAN antibody; MBTPS2 antibody; Membrane bound transcription factor site 2 protease antibody; membrane-bound transcription factor peptidase, site 2 antibody; membrane-bound transcription factor protease, site 2 antibody; Membrane-bound transcription factor site-2 protease antibody; S2P antibody; S2P endopeptidase antibody; Site 2 protease antibody; SREBPs intramembrane protease antibody; Sterol regulatory element-binding proteins intramembrane protease antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43462

Immunogen:Synthesized peptide derived from internal of Human MBTPS2.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IF; IF:1:100-1:500

Background:Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.

Rawson R.B., Mol. Cell 1:47-57(1997).
Ye J., Proc. Natl. Acad. Sci. U.S.A. 97:5123-5128(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MBTPS2

Research Areas:Cardiovascular?Cell biology;Metabolism;Signal transduction