MATK Monoclonal Antibody

SKU: BT-MCA4533

Size:100μL

Background:MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:MATK

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:9D7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MATK

Immunogen:Purified recombinant fragment of human MATK expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):56kDa

UniProt accession:P42679

Synonyms:CHK, CTK

GeneID:4145