MARCKS(Phospho-Ser159/163) Rabbit Polyclonal Antibody

SKU: BT-AP11241

Size:100μL

Background:The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility| phagocytosis| membrane trafficking and mitogenesis.

Research_area:Cardiovascular; Signal transduction

Target_protein:MARCKS

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MARCKS

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P29966; Mouse: P26645; Rat: P30009

Synonyms:MARCKS ;Ser159/163 ; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein; light chain; 80K-L protein; PKCSL

GeneID:Human: 4082; Mouse: 17118