LZTS1 Antibody - Cat. #: CSB-PA988963

SKU: CSB-PA988963

Size :50ul

Clone Number:

Aliases:F37 antibody; F37/esophageal cancer related gene coding leucine zipper motif antibody; F37/esophageal cancer-related gene-coding leucine-zipper motif antibody; Fez1 antibody; Leucine zipper putative tumor suppressor 1 antibody; Lzts1 antibody; LZTS1_HUMAN antibody; Psdzip70 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y250

Immunogen:Synthetic peptide of Human LZTS1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LZTS1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology