LRAT Antibody - Cat. #: CSB-PA295134

SKU: CSB-PA295134

Size :100ul

Clone Number:

Aliases:LCA14 antibody; Lecithin retinol acyltransferase (phosphatidylcholine retinol O acyltransferase) antibody; Lecithin retinol acyltransferase antibody; LRAT antibody; LRAT_HUMAN antibody; Phosphatidylcholine retinol O acyltransferase antibody; Phosphatidylcholine--retinol O-acyltransferase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95237

Immunogen:Synthesized peptide derived from internal of Human LRAT.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

Background:Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.

Ruiz A., J. Biol. Chem. 274:3834-3841(1999).
Mondal M.S., Biochemistry 39:5215-5220(2000).
Thompson D.A., Nat. Genet. 28:123-124(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LRAT

Research Areas:Neuroscience;Metabolism;Signal transduction