LMNA Polyclonal Antibody

SKU: E-AB-31899

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: Lamin A/C

Target Synonym: 70 kDa lamin;Cardiomyopathy dilated 1A (autosomal dominant);CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;Lamin A;Lamin A/C;Lamin A/C like 1;Lamin;Lamin C;Lamin-A/C;LDP1;LFP;LGMD1B;Limb girdle muscular dystrophy 1B (autosomal dominant);LMN 1;LMN A;LMN C;LMN1;LMNA;LMNA;LMNC;LMNL1;Prelamin A/C;PRO1;Renal carcinoma antigen NY REN 32;Renal carcinoma antigen NY-REN-32;Renal carcinoma antigen NYREN32

Research Areas: Cancer;Signal Transduction;Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P02545

Accession:

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser392.

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 74kDa

ObservedMW: 74kDa,65kDa