L1 Antibody, HRP conjugated - Cat. #: CSB-PA08349B0Rb

SKU: CSB-PA08349B0Rb

Size :50ug

Clone Number:

Aliases:L1 antibody; Major capsid protein L1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human) papillomavirus type 16

UniProt ID:P03101

Immunogen:Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA)

Raised in:Rabbit

Species Reactivity:Human papillomavirus type 16

Tested Applications:ELISA

Background:Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:L1

Research Areas:Cancer; Microbiology