(KO Validated) FGF2 Polyclonal Antibody

SKU: E-AB-93292

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:FGF2

Target Synonym:FGF2; BFGF; FGF-2; FGFB; HBGF-2; fibroblast growth factor 2

Research Areas:Cancer;Cardiovascular;Developmental Biology;Neuroscience;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P09038

Accession:

Background:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Concentration:1mg/mL

Immunogen:A synthetic peptide of human FGF2

Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:17kDa/21kDa/22kDa/30kDa

ObservedMW:18KDa/22KDa/24KDa