KMO Antibody - Cat. #: CSB-PA012475ESR1HU

SKU: CSB-PA012475ESR1HU

Size :50ul

Clone Number:

Aliases:dJ317G22.1 antibody; kmo antibody; KMO_HUMAN antibody; Kynurenine 3 hydroxylase antibody; Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase) antibody; Kynurenine 3 monooxygenase antibody; Kynurenine 3-hydroxylase antibody; Kynurenine 3-monooxygenase antibody; RP1-317G22.1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15229

Immunogen:Recombinant Human Kynurenine 3-monooxygenase protein (1-260AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background:Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KMO

Research Areas:Metabolism; Signal transduction