KCNQ5 Antibody - Cat. #: CSB-PA876430

SKU: CSB-PA876430

Size :100ul

Clone Number:

Aliases:KCNQ 5 antibody; KCNQ5 antibody; KCNQ5_HUMAN antibody; KQT like 5 antibody; KQT-like 5 antibody; Kv7.5 antibody; OTTHUMP00000064152 antibody; OTTHUMP00000064153 antibody; Potassium channel alpha subunit KvLQT5 antibody; Potassium channel protein antibody; Potassium channel subunit alpha KvLQT5 antibody; Potassium voltage gated channel KQT like subfamily member 5 antibody; Potassium voltage gated channel subfamily KQT member 5 antibody; Potassium voltage-gated channel subfamily KQT member 5 antibody; Voltage gated potassium channel subunit Kv7.5 antibody; Voltage-gated potassium channel subunit Kv7.5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NR82

Immunogen:Synthesized peptide derived from internal of Human KCNQ5.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M1 muscarinic receptors.

Lerche C., J. Biol. Chem. 275:22395-22400(2000).
Mungall A.J., Nature 425:805-811(2003).
Schroeder B.C., J. Biol. Chem. 275:24089-24095(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KCNQ5

Research Areas:Neuroscience