KCNQ4 Antibody - Cat. #: CSB-PA288698

SKU: CSB-PA288698

Size :100ul

Clone Number:

Aliases:DFNA 2 antibody; DFNA2 antibody; KCNQ 4 antibody; Kcnq4 antibody; KCNQ4_HUMAN antibody; KQT like 4 antibody; KQT-like 4 antibody; KV7.4 antibody; Potassium channel KQT like 4 antibody; Potassium channel subunit alpha KvLQT4 antibody; Potassium voltage gated channel KQT like protein 4 antibody; Potassium voltage gated channel KQT like subfamily member 4 antibody; Potassium voltage gated channel subfamily KQT member 4 antibody; Potassium voltage-gated channel subfamily KQT member 4 antibody; Voltage gated potassium channel subunit Kv7.4 antibody; Voltage-gated potassium channel subunit Kv7.4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P56696

Immunogen:Synthesized peptide derived from C-terminal of Human KCNQ4.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.

Kubisch C., Cell 96:437-446(1999).
Gregory S.G., Nature 441:315-321(2006).
Selyanko A.A., J. Physiol. (Lond.) 522:349-355(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KCNQ4

Research Areas:Neuroscience