KCNQ1 Polyclonal Antibody

SKU: E-AB-15154

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KCNQ1

Target Synonym: ATFB1;ATFB3;FLJ26167;IKs producing slow voltage-gated potassium channel subunit alpha;IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1;Jervell and Lange-Nielsen syndrome 1;JLNS1;KCNA8;KCNA9;KCNQ1;KCNQ1;kidney and cardiac voltage dependend K+ channel;KQT-like 1;Kv1.9;Kv7.1;KVLQT1;long (electrocardiographic) QT syndrome;Ward-Romano syndrome 1;LQT;LQT1;Potassium channel;voltage-gated;shaker-relatd subfamily;member 9;Potassium voltage-gated channel subfamily KQT member 1;potassium voltage-gated channel;KQT-like subfamily;member 1;RWS;slow delayed rectifier channel subunit;SQT2;Voltage-gated potassium channel subunit Kv7.1;WRS

Research Areas: Cancer;Cardiovascular;Metabolism;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P51787

Accession:

Background: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human KCNQ1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:200-1:1000;IHC 1:50-1:200

Calculated MW: 75kDa

ObservedMW: