ITK rabbit pAb

SKU: ES15411

Size: 100μL

Source:Rabbit

Applications:IHC;IF;WB

Reactivity:Human; Mouse

Dilution:IHC-p 1:50-200, WB 1:500-2000

Immunogen:Synthesized peptide derived from human ITK AA range: 450-530

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):72kD

Human_gene_id:3702

Human_swiss_prot_no:Q08881

Subcellular_location:Cytoplasm . Nucleus . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation.

Other_name:Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2;Interleukin-2-inducible T-cell kinase;IL-2-inducible T-cell kinase;Kinase EMT;T-cell-specific kinase;Tyrosine-protein kinase Lyk)

Background:This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008],