ITGB4 Monoclonal Antibody

SKU: BT-MCA4012

Size:100μL

Background:Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research_area:Signal Transduction

Target_protein:ITGB4

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:10B10D5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ITGB4

Immunogen:Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):202kDa

UniProt accession:P16144

Synonyms:CD104

GeneID: