Ipilimumab ELISA Kit

SKU: DB651018

Size:96T

Applications:ELISA

Accession:P16410

Stability and Storage:The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection method:Colorimetric

Sample type:Plasma, Serum

Assay type:Quantitative

Sensitivity:0.156 μg/ml

Range:0.31-5 μg/mL

Recovery:80-120%

Properties:

Experimental Procedure:

Background:Ipilimumab is a fully human IgG1 kappa antibody that binds to CTLA-4 (cytotoxic T lymphocyte associated antigen 4), a molecule on T cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses.

Alternative Names:BMS-734016, MDX-010, MDX-CTLA-4, 477202-00-9

Shipping:2-8 ℃

Note:For Research Use Only.