IMP cyclohydrolase Monoclonal Antibody

SKU: BT-MCA0776

Size:100μL

Background:This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Research_area:Epigenetics and nuclear signaling; Signal transduction; Metabolism

Target_protein:ATIC

applications:WB

Reactivity:Human,Rabbit

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Bifunctional purine biosynthesis protein PURH

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: P31939; Mouse: Q9CWJ9; Rat: O35567

Synonyms:ATIC; PURH; OK; SW-cl.86; Bifunctional purine biosynthesis protein PURH

GeneID:Human: 471