IL13 Antibody - Cat. #: CSB-PA011590KA01HU

SKU: CSB-PA011590KA01HU

Size :100ul

Clone Number:

Aliases:Allergic rhinitis antibody; ALRH antibody; BHR 1 antibody; BHR1 antibody; Bronchial hyperresponsiveness 1 (bronchial asthma) antibody; IL 13 antibody; IL-13 antibody; Il13 antibody; IL13_HUMAN antibody; Interleukin 13 antibody; Interleukin-13 antibody; interleukin13 antibody; MGC116786 antibody; MGC116788 antibody; MGC116789 antibody; NC 30 antibody; NC30 antibody; P 600 antibody; P600 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35225

Immunogen:Recombinant protein of Human IL13

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200

Background:IL-13 is produced by T cells and is important in the TH2 response. IL-13 targets include B cells, eosinophils, fibroblasts, mast cells and macrophages. IL-13 binds specifically to IL-13R?1 that complexes with IL-4R? to form the Type II IL-4R. Jak1 and Tyk2 are activated and signal through Stat3 and Stat6. IL-13R?2 is a different gene product, lacks the intracellular domain, does not complex with IL-4R? and does not signal. The extracellular domain of IL-13R?2 is often elevated in diseased states. IL-13 plays key roles in airway hyperresponsiveness (AHR) of allergic asthma and modulates resistance to parasitic organisms.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Affinity purification

Conjugate:Non-conjugated

Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IL13

Research Areas:Cancer?Cardiovascular;Immunology