IL12RB2 Antibody - Cat. #: CSB-PA953263

SKU: CSB-PA953263

Size :50ul

Clone Number:

Aliases:I12R2_HUMAN antibody; IL-12 receptor subunit beta-2 antibody; IL-12R subunit beta-2 antibody; IL-12R-beta-2 antibody; IL-12RB2 antibody; IL12 receptor beta 2 antibody; IL12R beta2 antibody; IL12RB2 antibody; Interleukin 12 receptor beta 2 antibody; Interleukin 12 receptor beta 2 chain antibody; Interleukin-12 receptor subunit beta-2 antibody; RP11 102M16.1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99665

Immunogen:Synthetic peptide of Human IL12RB2

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IL12RB2

Research Areas:Cancer;Immunology