IL10RB antibody , Cat. # FNab04215

SKU: FNab04215

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.

Immunogen:interleukin 10 receptor, beta

Synonyms:CRFB4, D21S58, D21S66

Observed MW:42-45 kDa

Uniprot ID:Q08334

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:3588

Research Area:Immunology, Cardiovascular, Signal Transduction