Human Wilms Tumor Protein 1,WT1 ELISA KIT

SKU: E3811Hu

Size:96 Tests-1 Kit

Background:Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921). {ECO:0000269|PubMed:15520190, ECO:0000269|PubMed:16934801, ECO:0000269|PubMed:17716689, ECO:0000269|PubMed:19123921, ECO:0000269|PubMed:19416806, ECO:0000269|PubMed:25258363, ECO:0000269|PubMed:7862533}.

Research_area:

Applications:ELISA

Target_protein:WT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.03ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Wilms Tumor Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P19544

MASS(Da):49188

GeneID:7490

Synonyms:WT1

Gene names:WT1

Standard solution:32ng/ml