Human WD Repeat-containing Protein 1,WDR1 ELISA KIT

SKU: E7480Hu

Size:96 Tests-1 Kit

Background:Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458, PubMed:27557945, PubMed:29751004). Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565). {ECO:0000250|UniProtKB:O88342, ECO:0000250|UniProtKB:Q9W7F2, ECO:0000269|PubMed:15629458, ECO:0000269|PubMed:18494608, ECO:0000269|PubMed:25792565, ECO:0000269|PubMed:27557945, ECO:0000269|PubMed:29751004}.

Research_area:

Applications:ELISA

Target_protein:WDR1

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.06ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:WD Repeat-containing Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O75083

MASS(Da):66194

GeneID:9948

Synonyms:WDR1

Gene names:WDR1

Standard solution:3200ng/L