Human Von Hippel-lindau Disease Tumor Suppressor, VHL ELISA Kit

SKU: E6401Hu

Size:96 Tests-1 Kit

Background:Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.

Research_area:Others

Applications:ELISA

Target_protein:VHL

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.03ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Von Hippel-Lindau disease tumor suppressor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P40337

MASS(Da):24,153

GeneID:7428

Synonyms:HRCA1;Protein G7;pVHL;RCA1;VHL;VHL1;von Hippel-Lindau disease tumor suppressor

Gene names:VHL

Standard solution:3200ng/L